Non-Invasive Prenatal Test: NIPT +

At LabGenetics, in our commitment to offering the most advanced technology available, we have developed the Non-Invasive Prenatal Test (NIPT) Complete Plus, a 100% safe test that analyzes cell-free fetal DNA present in the blood of the pregnant mother. This technique offers the major advantage of posing no risk to the fetus.

This test allows for the detection or exclusion in the fetus of trisomies/aneuploidies involving chromosomes 21 (Down Syndrome), 18 (Edwards Syndrome), 13 (Patau Syndrome), and sex chromosomes X and Y (including Turner Syndrome XO, Klinefelter Syndrome XXY, Triple X Syndrome, Jacobs Syndrome XYY), as well as the screening of up to 93 microdeletion/microduplication syndromes.

Additionally, fetal sex can also be determined.

The test can be performed from the 12th week of gestation onwards, with the optimal window between weeks 12 and 22+6 of pregnancy.

The turnaround time for results is approximately 12–15 working days, starting from the day after sample collection.

For the analysis, at least 10 ml of maternal peripheral blood is required. Please contact us to arrange the most suitable day for blood collection at our facilities.

Blood transfusions (allogeneic transfusions), organ or bone marrow transplants, and allogeneic cell therapies, among others, may introduce exogenous sources of DNA that could compromise the results. In cases of recent spontaneous miscarriage or embryonic reduction, residual fetal DNA may remain, which could affect the accuracy of the test. This test is not suitable for multiple pregnancies (more than two fetuses), nor for pregnant women with oncological conditions, preeclampsia, or congenital autoimmune diseases.

A gestational age of less than 12 weeks, or an inaccurate estimation of gestational age, may result in insufficient fetal genetic material to obtain a reliable result.

The Non-Invasive Prenatal Test is contraindicated in the following cases:

If you have received an allogeneic blood transfusion (donated blood from another person) within the last year
If you have undergone a bone marrow or organ transplant, or stem cell therapy within the last year
If you have received therapies involving exogenous DNA, immunotherapy, cellular therapy, etc., within the last month
If you have experienced a spontaneous miscarriage within the last three months
If you have undergone embryonic reduction (termination of one or more fetuses in a multiple pregnancy)
If the pregnancy was achieved through surrogacy
If you have undergone in vitro fertilization (IVF)
If the gestational age is less than 12 weeks or greater than 22+6 weeks
If it is a multiple pregnancy

View here all syndromes that can be ruled out or confirmed with this test. View here all syndromes that can be ruled out or confirmed with this test.

Trisomy 21 (Down Syndrome)
Turner Syndrome (XO)
Jacobs Syndrome (XYY)
1p36 Deletion Syndrome
22q11.2 Deletion Syndrome (DiGeorge Syndrome)
Smith-Magenis Syndrome
1p32-p31 Deletion Syndrome
1q25.2-q32.1 Deletion Syndrome
1q23-q41 Duplication Syndrome
1q31-proximal telomeric Duplication Syndrome
1q41-q42 Deletion Syndrome
1q43-q44 Deletion Syndrome
2p25.3 Deletion Syndrome
2p25.3 Duplication Syndrome
2pter-p24.1 Duplication Syndrome
2p16.1-p15 Deletion Syndrome
2p12-p11.2 Deletion Syndrome
2q33.1 Deletion Syndrome
2q32.3-q37.3 Duplication Syndrome
2q37 Deletion Syndrome
3pter-p25 Deletion Syndrome
3pter-p24.3 Duplication Syndrome
Dandy-Walker Syndrome
3qter-q24 Duplication Syndrome
4p Duplication Syndrome
4q21 Deletion Syndrome
4q distal Duplication Syndrome
4q32.1-q32.2 Duplication Syndrome
4q distal Deletion Syndrome
5p Duplication Syndrome
5q12 Deletion Syndrome
5q14.3 Deletion Syndrome
6pter-p23 Duplication Syndrome
6q11-q14 Deletion Syndrome
Trisomy 18 (Edwards Syndrome)
Klinefelter Syndrome (XXY)
Wolf-Hirschhorn Syndrome
Prader-Willi Syndrome
6q24-q25 Deletion Syndrome
6q Deletion Syndrome
7q Duplication Syndrome
7qter-q32 Deletion Syndrome
REC8 Recombination Syndrome (deletion)
8p23.1 Deletion Syndrome
8p23.1 Duplication Syndrome
8p Duplication Syndrome
8q22.1 Deletion Syndrome
REC8 Recombination Syndrome (duplication)
Langer-Giedion Syndrome
8qter-q24.13 Duplication Syndrome
9p Duplication Syndrome
9p Deletion Syndrome
10p15.3-p13 Duplication Syndrome
DiGeorge Syndrome Type 2
10q22.3-q23.2 Deletion Syndrome
10q Duplication Syndrome
10q26 Deletion Syndrome
WAGR Syndrome (11p13 deletion)
Potocki-Shaffer Syndrome
11q proximal telomeric Deletion Syndrome
Jacobsen Syndrome
Tetrasomy 12p Syndrome
12q14 Deletion Syndrome
13q14 Deletion Syndrome
13q Duplication Syndrome
13q Deletion Syndrome
14q11-q22 Deletion Syndrome
Trisomy 13 (Patau Syndrome)
Triple X Syndrome (XXX)
Cri du Chat Syndrome
Angelman Syndrome
14q Duplication Syndrome
15q14 Deletion Syndrome
15q24 Duplication Syndrome
15q24 Deletion Syndrome
15q22-qter Duplication Syndrome
15q25 Deletion Syndrome
15q26 Duplication Syndrome
15qter-q26 Deletion Syndrome
16p13.3 Duplication Syndrome
16p12.2-p11.2 Deletion Syndrome
16q22 Deletion Syndrome
16p Duplication Syndrome
17p13.3 proximal telomeric Duplication Syndrome
Yuan-Harel-Lupski Syndrome
Potocki-Lupski Syndrome
18p Deletion Syndrome
18p Duplication Syndrome
18q Deletion Syndrome
18q Duplication Syndrome
18q Proximal Deletion Syndrome
Alagille Syndrome
20p Duplication Syndrome
21q11.2-q21.3 Deletion Syndrome
Cat Eye Syndrome
Xp Duplication Syndrome
Xp Deletion Syndrome
Xq Duplication Syndrome
Xq23-qter Deletion Syndrome
Xq27.3-q28 Duplication Syndrome

At LabGenetics, in our commitment to offering the most advanced technology available, we have developed the Non- Invasive Prenatal Test (NIPT) Complete Plus, a 100% safe test that analyzes cell-free fetal DNA present in the blood of the pregnant mother. This technique offers the major advantage of posing no risk to the fetus.

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LabGenetics offers a comprehensive genetic diagnostic service, personalized, flexible to the requirements of health professionals, and continuously introduces new genetic diagnostics of hereditary and rare diseases in its portfolio of services. Our goal is to establish close collaborations that allow us to obtain accurate and appropriate results for each case, as quickly and economically as possible.