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Oncologic and neoplastic diseases (cancer)

AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME: 38 genes – Delivery time: 3-4 weeks

ADA2, AICDA, CARD11, CASP10, CASP8, CD40LG, CTLA4, DEF6, FADD, FAS, FASLG, IL2RA, ITK, KRAS, LRBA, LYST, MAGT1, MYO5A, NRAS, PIK3CD, PIK3R1, PRF1, PRKCD, RAB27A, RASGRP1, RECQL4, SH2D1A, STAT3, STK4, STX11, STXBP2, TET2, TNFAIP3, TNFRSF9, TPP2, UNC13D, WAS, XIAP

BLACKFAN-DIAMOND ANEMIA: 21 genes – Delivery time: 3-4 weeks

EPO, GATA1, RPL11, RPL15, RPL26, RPL27, RPL35A, RPL36, RPL5, RPS10, RPS15, RPS17, RPS19, RPS24, RPS26, RPS27, RPS27A, RPS28, RPS29, RPS7, TSR2

BONE AND SOFT TISSUE CANCER (SARCOMA AND OSTEOSARCOMA): 33 genes – Delivery time: 3-4 weeks

APC, BLM, CDKN1C, CDKN2A, DICER1, EPCAM, EXT1, EXT2, FH, FN1, HRAS, KIT, MLH1, MSH2, MSH6, NBN, NF1, PDGFRA, PMS2, PRKAR1A, PTCH1, PTCH2, RB1, RECQL4, SDHA, SDHB, SDHC, SDHD, SUFU, TP53, TSC1, TSC2, WRN

BREAST AND OVARIAN CANCER: 51 genes – Delivery time: 3-4 weeks

APC, ATM, ATR, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDKN2A, CHEK2, CYP17A1, EPCAM, ERCC2, ERCC4, FANCC, FANCD2, FANCI, FANCM, HOXB13, MEN1, MLH1, MLH3, MRE11, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, PALB2, PMS1, PMS2, PPM1D, PSMC3IP, PTEN, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RECQL, SLX4, SMARCA4, STK11, TNFRSF13B, TP53, WRN, XRCC2, XRCC3

CANCER OF THE CENTRAL NERVOUS SYSTEM AND BRAIN: 41 genes – Delivery time: 3-4 weeks

AIP, ALK, APC, ATM, BAP1, BARD1, BRCA2, CDKN1B, CDKN2A, DICER1, EPCAM, EZH2, GPC3, HRAS, KIF1B, LZTR1, MEN1, MLH1, MSH2, MSH6, NBN, NF1, NF2, PHOX2B, PMS2, POT1, PRKAR1A, PTCH1, PTCH2, PTEN, RB1, SETD2, SMARCA4, SMARCB1, SMARCE1, SUFU, TP53, TSC1, TSC2, VHL, WRN

CONGENITAL DYSKERATOSIS: 15 genes – Delivery time: 3-4 weeks

AK2, CTC1, DKC1, GRHL2, LIG4, NHP2, NOP10, PARN, POT1, RTEL1, TERT, TINF2, TYMS, USB1, WRAP53

COWDEN DISEASE/COWDEN-LIKE: 9 genes – Delivery time: 3-4 weeks

AKT1, BMPR1A, KLLN, PIK3CA, PTEN, SDHB, SDHC, SDHD, SEC23B

FAMILIAR ADENOMATOUS POLYPOSIS (FAP) & JUVENILE POLYPOSIS: 24 genes – Delivery time: 3-4 weeks

APC, AXIN2, BMPR1A, BRCA1, BRCA2, DIS3L2, ENG, EZH2, GALNT12, GREM1, MLH1, MSH2, MSH3, MSH6, MUTYH, NTHL1, PIK3CA, PMS2, POLD1, POLE, PTEN, SCG5, SMAD4, STK11

FAMILIAR PITUITARY ADENOMA/ PROLACTINOMA: 15 genes – Delivery time: 3-4 weeks

AIP, CDH23, CDKN1B, CDKN2A, CDKN2C, GNAS, GPR101, MEN1, POU1F1, PRKAR1A, PRKCA, SDHA, SDHB, SDHC, SDHD

FAMILY PROSTATE CANCER: 33 genes – Delivery time: 3-4 weeks

ABRAXAS1, APC, AR, ATM, ATR, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, EPCAM, FANCA, FANCD2, FANCM, GEN1, HOXB13, MLH1, MRE11, MSH2, MSH6, MSR1, MUTYH, NBN, PALB2, PMS1, PMS2, PTEN, RAD51C, RAD51D, RNASEL, STK11, TP53

FANCONI ANEMIA: 26 genes – Delivery time: 3-4 weeks

ATM, ATR, BLM, BRCA1, BRCA2, BRIP1, CXCR4, ERCC4, ERCC6L2, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, NBN, PALB2, RAD51, RAD51C, SLX4, UBE2T, XRCC2

GLOBAL HEREDITARY CANCER: 282 genes – Delivery time: 3-4 weeks

ABRAXAS1, ACVRL1, AIP, AKT1, ALK, ANKRD26, APC, APOA1, APOA2, AR, ARID1A, ATM, ATR, ATRX, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRAF, BRCA1, BRCA2, BRIP1, BTK, BUB1, BUB1B, CABIN1, CARD11, CASP10, CASP8, CASR, CBL, CCND1, CD27, CD40LG, CDC73, CDH1, CDK4, CDKN1B, CDKN1C, CDKN2A, CDKN2B, CEBPA, CEP57, CHEK2, COQ6, CREBBP, CSF3R, CST3, CTC1, CTLA4, CTNNA1, CTPS1, CTRC, CYLD, DDB2, DICER1, DIS3L2, DKC1, DLST, DOCK8, EGFR, EGLN1, ELANE, EP300, EPAS1, EPCAM, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, ERCC6L2, ETV6, EXO1, EXT1, EXT2, EZH2, FADD, FAM111B, FAN1, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FAS, FASLG, FERMT1, FGA, FH, FLCN, FN1, FOXE1, G6PC3, GALNT12, GATA2, GCM2, GDNF, GFI1, GPC3, GPC4, GPR101, GREM1, GSN, HABP2, HAX1, HNF1A, HNF1B, HOXA11, HOXB13, HRAS, IDH1, IKZF1, IL1B, IL1RN, ITK, JAGN1, JAK2, KDM1A, KIF1B, KIT, KITLG, KMT2D, KRAS, LIG4, LYZ, LZTR1, MAGT1, MAP2K1, MAP2K2, MAX, MBD4, MC1R, MDH2, MECOM, MEN1, MET, MINPP1, MITF, MLH1, MLH3, MNX1, MPL, MRE11, MRTFA, MSH2, MSH3, MSH6, MSR1, MUTYH, NBN, NDUFA13, NF1, NF2, NFIX, NHP2, NOP10, NPAT, NPM1, NRAS, NSD1, NSUN2, NTHL1, NTRK1, NUDT1, OGG1, PALB2, PALLD, PARN, PAX5, PAX6, PC, PDE11A, PDE8B, PDGFRA, PGM3, PHOX2B, PIK3CA, PIK3CD, PMS1, PMS2, POLD1, POLE, POLH, POT1, PPM1D, PRCC, PRF1, PRKAR1A, PRSS1, PSMC3IP, PTCH1, PTCH2, PTEN, PTPN11, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RAF1, RASA2, RASGRP1, RB1, RBM8A, RECQL, RECQL4, REST, RET, RHBDF2, RIT1, RNASEL, RNF139, RPL11, RPL35A, RPS24, RRAS, RTEL1, RUNX1, SAMD9, SBDS, SCG5, SDHA, SDHAF2, SDHB, SDHC, SDHD, SEC23B, SH2B3, SH2D1A, SHOC2, SLC45A2, SLX4, SMAD4, SMARCA2, SMARCA4, SMARCB1, SMARCE1, SOS1, SOS2, SPINK1, SPRED1, SRP72, STAT3, STK11, SUFU, TERT, TET2, TGFBR1, TGFBR2, THPO, TINF2, TMEM127, TNFRSF13B, TNFRSF9, TP53, TRIP13, TSC1, TSC2, TTR, TYR, UBE2T, UNC13D, USB1, VHL, VPS45, WAS, WRAP53, WRN, WT1, XIAP, XPA, XPC, XRCC2, XRCC3

HEREDITARY COLORECTAL CANCER: 41 genes – Delivery time: 3-4 weeks

AKT1, APC, ATM, AXIN2, BLM, BMPR1A, BRCA1, BRCA2, BUB1, CDC73, CDH1, CHEK2, CTNNA1, DIS3L2, EPCAM, FAN1, GALNT12, GREM1, MLH1, MLH3, MSH2, MSH3, MSH6, MUTYH, NTHL1, PIF1, PIK3CA, PMS1, PMS2, POLD1, POLE, PTEN, RBL1, SCG5, SMAD4, STK11, TELO2, TGFBR2, TP53, TSC1, TSC2

HEREDITARY ENDOCRINE CANCER: 31 genes – Delivery time: 3-4 weeks

AIP, APC, CASR, CDC73, CDKN1B, CHEK2, DICER1, FH, HABP2, KIF1B, MAX, MEN1, MET, NF1, NTRK1, PHOX2B, PRKAR1A, PTEN, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, SEC23B, TMEM127, TP53, TSC1, TSC2, VHL, WRN

HEREDITARY ENDOMETRIAL CANCER: 13 genes – Delivery time: 3-4 weeks

BRCA1, BRCA2, CHEK2, EPCAM, MLH1, MSH2, MSH6, MUTYH, PMS2, POLD1, PTEN, STK11, TP53

HEREDITARY GASTROINTESTINAL CANCER: 52 genes – Delivery time: 3-4 weeks

APC, ATM, AXIN2, BAP1, BLM, BMPR1A, BRCA1, BRCA2, BUB1B, CDH1, CDKN1B, CDKN2A, CHEK2, CTNNA1, EPCAM, FANCC, GALNT12, GREM1, KIT, MAP3K6, MEN1, MLH1, MLH3, MSH2, MSH3, MSH6, MSR1, MUTYH, NF1, NTHL1, PALB2, PC, PDGFRA, PMS1, PMS2, POLD1, POLE, PTEN, RHBDF2, SDHA, SDHB, SDHC, SDHD, SMAD4, SMARCB1, STK11, TMEM127, TP53, TSC1, TSC2, VHL, WRN

HEREDITARY LEUKEMIA AND MYELODYSPLASTIC SYNDROMES: 81 genes – Delivery time: 3-4 weeks

ANKRD26, ASXL1, ATM, BCL2, BLM, BRAF, BRCA1, BRCA2, BRIP1, BTK, CBL, CDKN2A, CEBPA, CHD2, CHEK2, CREBBP, DKC1, DNMT3A, EGR2, ELANE, EPCAM, ERCC6L2, ETV6, EZH2, FANCA, FBXW7, FLT3, G6PC3, GATA2, GFI1, HAX1, HRAS, IDH1, IDH2, IKZF1, IKZF3, IRF4, JAK2, KIT, KRAS, MAP2K1, MAP2K2, MECOM, MLH1, MSH2, MSH6, MYD88, NBN, NF1, NOTCH1, NPM1, NRAS, PALB2, PAX5, PDGFRB, PHF6, PMS2, POT1, PTPN11, RAD21, RIT1, RPS15, RTEL1, RUNX1, SAMD9, SAMHD1, SBDS, SF3B1, SMC1A, SMC3, SOS1, SRP72, SRSF2, STAG2, TERT, TET2, TINF2, TP53, U2AF1, WT1, XPO1

HEREDITARY MELANOMA/SKIN CANCER: 34 genes – Delivery time: 3-4 weeks

BAP1, BRCA1, BRCA2, BRIP1, CDK4, CDKN2A, CDKN2B, CHEK2, DDB2, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, MC1R, MITF, MUTYH, NBN, POLE, POLH, POT1, PTCH1, PTEN, RB1, SLC45A2, SUFU, TERT, TP53, TYR, WRN, XPA, XPC, XRCC2, XRCC3

HEREDITARY PANCREAS CANCER: 35 genes – Delivery time: 3-4 weeks

AKT1, APC, ATM, BMPR1A, BRCA1, BRCA2, BUB1B, CASR, CDC73, CDK4, CDKN1B, CDKN2A, CFTR, CHEK2, CTRC, EPCAM, FANCA, FANCC, MEN1, MLH1, MSH2, MSH6, NF1, PALB2, PALLD, PMS1, PMS2, PRSS1, SMAD4, SPINK1, STK11, TP53, TSC1, TSC2, VHL

HEREDITARY RENAL/URINARY CANCER: 40 genes – Delivery time: 3-4 weeks

BAP1, BUB1B, CDC73, CDKN1C, CEP57, CHEK2, DICER1, DIS3L2, EPCAM, FH, FLCN, GPC3, HNF1A, HNF1B, HRAS, MET, MITF, MLH1, MSH2, MSH6, MUTYH, PALB2, PBRM1, PMS1, PMS2, PRCC, PTEN, REST, RNF139, SDHA, SDHB, SDHC, SDHD, SMARCA4, SMARCB1, TP53, TSC1, TSC2, VHL, WT1

HEREDITARY THYROID CANCER: 17 genes – Delivery time: 3-4 weeks

APC, CDC73, CHEK2, DICER1, FOXE1, HABP2, MEN1, MINPP1, NTRK1, PRKAR1A, PTEN, RET, SDHB, SDHD, SEC23B, TP53, WRN

MEDULOBLASTOMA: 14 genes – Delivery time: 3-4 weeks

APC, BRCA2, ELP1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, PTCH1, PTCH2, SMARCB1, SUFU, TP53

MULTIPLE ENDROCRINE NEOPLASM: 9 genes – Delivery time: 3-4 weeks

AIP, CASR, CDC73, CDKN1A, CDKN1B, CDKN2B, CDKN2C, MEN1, RET

NEUROFIBROMATOSIS/ SCHWANNOMATOSIS: 16 genes – Delivery time: 3-4 weeks

CABIN1, CCND1, COQ6, KIT, KITLG, LZTR1, NF1, NF2, PRKAR1A, PTPN11, RAF1, SMARCB1, SPRED1, TSC1, TSC2, VHL

OVARIAN CANCER: 31 genes – Delivery time: 3-4 weeks

ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK1, CHEK2, DICER1, EPCAM, FANCA, FANCM, MLH1, MRE11, MSH2, MSH6, MUTYH, NBN, NF1, PALB2, PMS1, PMS2, PTEN, RAD1, RAD50, RAD51C, RAD51D, SMARCA4, STK11, TP53, TP53I3

PARAGANGLIOMA AND PHEOCHROMOCYTOMA: 27 genes – Delivery time: 3-4 weeks

ATRX, CDC73, CDKN1B, DLST, EGLN1, EPAS1, FH, GDNF, HRAS, IDH1, KIF1B, KMT2D, MAX, MDH2, MEN1, MET, NF1, PRKAR1A, RET, SDHA, SDHAF1, SDHAF2, SDHB, SDHC, SDHD, TMEM127, VHL

PEDIATRIC CANCER: 168 genes – Delivery time: 3-4 weeks

ABL1, ABL2, ACVR1, AKT1, ALK, ANKRD26, APC, ARID1A, ARID1B, ASXL1, ATM, ATRX, AXIN2, BAP1, BLM, BMPR1A, BRAF, BUB1B, CALR, CBL, CCND3, CCR5, CDC73, CDK4, CDKN1C, CDKN2A, CDKN2B, CEBPA, CHD7, CIC, CREBBP, CRLF1, CSF1R, CSF3R, CTNNB1, DAXX, DDX3X, DICER1, DIS3L2, DNMT3A, EGFR, EP300, EPCAM, ERBB2, ERBB3, ERBB4, ESR1, ETV6, EXT1, EXT2, EZH2, FAS, FASLG, FBXW7, FGFR2, FGFR3, FH, FLT3, GATA1, GATA2, GATA3, GNA11, GNA13, GNAQ, GPC3, HDAC9, HRAS, ID3, IDH1, IDH2, IKZF1, IL7R, JAK1, JAK2, JAK3, KDM4C, KDM6A, KDR, KIF1B, KIT, KMT2D, KRAS, LZTR1, MAP2K1, MAP2K2, MAX, MEN1, MET, MLH1, MPL, MSH2, MSH6, MTOR, MYOD1, NBN, NF1, NF2, NOTCH1, NPM1, NRAS, NSD1, NSD2, NSUN2, NT5C2, PAX5, PDGFRA, PDGFRB, PHF6, PHOX2B, PIK3CA, PIK3R1, PMS2, POT1, PPM1D, PRF1, PRKAR1A, PRPS1, PTCH1, PTCH2, PTEN, PTPN11, RAF1, RASA2, RB1, RECQL4, REST, RET, RIT1, RRAS, RUNX1, SDHA, SDHAF2, SDHB, SDHC, SDHD, SETBP1, SETD2, SH2B3, SH2D1A, SHOC2, SMAD4, SMARCA4, SMARCB1, SMARCE1, SMO, SOS1, SOS2, SRP72, STAT3, STAT5B, STK11, SUFU, SUZ12, TCF3, TERT, TET2, TMEM127, TP53, TPMT, TRIP13, TSC1, TSC2, USP7, VHL, WRN, WT1, XIAP, ZMYM3

PHEOCHROMOCYTOMA AND PARAGANGLIOMA: 27 genes – Delivery time: 3-4 weeks

ATRX, CDC73, CDKN1B, DLST, EGLN1, EPAS1, FH, GDNF, HRAS, IDH1, KIF1B, KMT2D, MAX, MDH2, MEN1, MET, NF1, PRKAR1A, RET, SDHA, SDHAF1, SDHAF2, SDHB, SDHC, SDHD, TMEM127, VHL

PREDISPOSITION TO PEDIATRIC SOLID TUMORS: 106 genes – Delivery time: 3-4 weeks

AIP, ALK, APC, ATM, AXIN2, BAP1, BLM, BMPR1A, BRAF, BRCA2, BRIP1, BUB1B, CBL, CDC73, CDKN1C, CEBPA, CREBBP, CTC1, DDB2, DICER1, DIS3L2, DKC1, EP300, EPCAM, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, EXT1, EXT2, EZH2, FANCA, FANCE, FANCG, FERMT1, FH, FLCN, GATA2, GPC3, GPC4, HRAS, KRAS, LZTR1, MAP2K1, MAP2K2, MAX, MEN1, MLH1, MSH2, MSH6, NBN, NF1, NF2, NRAS, NSD1, NSUN2, PAX5, PAX6, PHOX2B, PIK3CA, PMS2, POLH, POT1, PRF1, PRKAR1A, PTCH1, PTEN, PTPN11, RAF1, RASA2, RB1, RECQL4, REST, RET, RIT1, RRAS, RTEL1, RUNX1, SBDS, SDHA, SDHAF2, SDHB, SDHC, SDHD, SHOC2, SMAD4, SMARCA4, SMARCB1, SMARCE1, SOS1, SOS2, STK11, SUFU, TERT, TINF2, TMEM127, TP53, TSC1, TSC2, USB1, VHL, WRN, WT1, XPA, XPC

SCHWANNOMATOSIS/ NEUROFIBROMATOSIS: 16 genes – Delivery time: 3-4 weeks

CABIN1, CCND1, COQ6, KIT, KITLG, LZTR1, NF1, NF2, PRKAR1A, PTPN11, RAF1, SMARCB1, SPRED1, TSC1, TSC2, VHL

UTERUS/ENDOMETRIAL CANCER: 27 genes – Delivery time: 3-4 weeks

APC, ATM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDKN2A, CHEK2, CTNNB1, EPCAM, MLH1, MSH2, MSH6, MUTYH, NBN, PALB2, PIK3CA, PMS2, POLD1, POLE, PTEN, RAD51C, SMAD4, STK11, TP53, VHL

WILMS TUMOR: 37 genes – Delivery time: 3-4 weeks

AMER1, ARID1A, ASXL1, BLM, BRCA2, BUB1B, CDC73, CDKN1C, CHD4, COL6A3, CTNNB1, DGCR8, DICER1, DIS3L2, DROSHA, EP300, FBXW7, GPC3, GPC4, HACE1, HDAC4, IGF2, NF1, PALB2, PIK3CA, POU6F2, REST, RLIM, SIX1, SIX2, SMARCA4, TP53, TRIM28, TRIM37, TRIP13, WT1, XPO5

XERODERMA PIGMENTOUS: 10 genes – Delivery time: 3-4 weeks

DDB2, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, POLH, XPA, XPC

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