Pharmacogenetics

CLINICAL RESPONSE TO ACENOCUMAROL (SINTROM): 3 genes – Delivery time: 3-4 weeks

CYP2C9, CYP4F2, VKORC1

CLINICAL RESPONSE TO ANTICOAGULANTS – ACENOCUMAROL, WARFARIN: 3 genes – Delivery time: 3-4 weeks

CYP2C9, CYP4F2, VKORC1

CLINICAL RESPONSE TO ANTIDEPRESSANTS – AMITRIPTYLINE, BUPROPION, CITALOPRAM, CLOMIPRAMINE, DESIPRAMINE, DOXEPIN, ESCITALOPRAM, FLUVOXAMINE, IMIPRAMINE, MIRTAZAPINE, NORTRIPTYLINE, PAROXETINE, RISPERIDONE, SERTRALINE, TRIMIPRAMINE, VENLAFAXINE, VORTIOXETINE: 3 genes – Delivery time: 3-4 weeks

CYP2B6, CYP2C19, CYP2D6

CLINICAL RESPONSE TO ANTINEOPLASTIC AGENTS – AZATHIOPRINE, CAPECITABINE, FLUOROURACIL, IRINOTECAN, METHOTREXATE, TAMOXIFEN: 7 genes – Delivery time: 3-4 weeks

CYP2D6, DPYD, MTHFR, NUDT15, SLC19A1, TPMT, UGT1A1

CLINICAL RESPONSE TO ANTIPSYCHOTICS – ARIPIPRAZOLE, HALOPERIDOL, QUETIAPINE, ZUCLOPENTHIXOL: 2 genes – Delivery time: 3-4 weeks

CYP2D6, CYP3A4

CLINICAL RESPONSE TO CARDIOVASCULAR AGENTS: 7 genes – Delivery time: 3-4 weeks

ABCG2, CYP2C19, CYP2C9, CYP2D6, CYP4F2, SLCO1B1, VKORC1

CLINICAL RESPONSE TO DRUGS METABOLIZED BY P450 ENZYME FAMILY: 8 genes – Delivery time: 3-4 weeks

CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5, SLCO1B1, VKORC1

CLINICAL RESPONSE TO DRUGS, COMPRENHENSIVE: 54 genes – Delivery time: 3-4 weeks

ABCB1, ABCC2, ABCG2, ACE, ADRB1, ADRB2, ANKK1, APOE, BCHE, CACNA1S, CES1, CFTR, COMT, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A5, CYP4F2, DPYD, DRD2, G6PD, GSTM1, GSTP1, GSTT1, HLA-A, HLA-B, HMGCR, IFNL3, ITPA, KIF6, MTHFR, NAT2, NQO1, NUDT15, OPRM1, PTGS2, RYR1, SCN1A, SLC19A1, SLC22A1, SLCO1B1, TPMT, TYMS, UGT1A1, VKORC1, XRCC1

CLINICAL RESPONSE TO FLUVASTATIN: 2 genes – Delivery time: 3-4 weeks

CYP2C9, SLCO1B1

CLINICAL RESPONSE TO INHALED ANESTHETICS- DESFLURANE, ENFLURANE, ISOFLURANE, SEVOFLURANE, METHOXYFLURANE: 2 genes – Delivery time: 3-4 weeks

CACNA1S, RYR1

CLINICAL RESPONSE TO NEUROPSYCHIATRIC AGENTS: 5 genes – Delivery time: 3-4 weeks

CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4, HLA-A*31:01, HLA-B*15:02, HLA-B*15:11

CLINICAL RESPONSE TO OPIOID ANALGESICS – CODEINE, FENTANYL, METHADONE, OXYCODONE, TRAMADOL: 3 genes – Delivery time: 3-4 weeks

CYP2B6, CYP2D6, CYP3A4

CLINICAL RESPONSE TO PAIN-RELIEF DRUGS: 4 genes – Delivery time: 3-4 weeks

CYP2B6, CYP2C9, CYP2D6, CYP3A4

CLINICAL RESPONSE TO ROSUVASTATIN: 2 genes – Delivery time: 3-4 weeks

ABCG2, SLCO1B1